文档介绍：· 52· 神经疾病与精神卫生2021年1月20日第21卷第1期 Journal of Neuroscience and Mental Health， January 20，2021，，
dition to the core symptoms of social interaction disorder， cognitive impairment and repetitive stereotyped
behavior， there are also obvious multi-sensory abnormalities. ASD patients with abnormal pain will make
repetitive self-injurious behavior， which not only causes serious harm to patients but also their families， causing
widespread concern of families and society. Further study on the pain sensitivity of children and the principle
and mechanism of pain sensitivity can not only reduce the pain experience of children， but also provide new
ideas for the treatment of children with ASD. This paper reviewed the recent studies on the epidemiology，
clinical trials， genetics， imaging and the pain sensitivity of ASD animal models. The future study could focus on
the optimal intervention scheme， and provide theoretical basis for further clinical promotion.
【Key words】 Autism spectrum disorders； Pain sensitivity； Mechanism； Review
Fund programs： Scientific Research Project Approved by Health and Family Planning Commission
of Heilongjiang Province（2017 -166）； Fundamental Research Funds for Heilongjiang Provincial Universities
（2018-KYYWF-0440）
孤 独 症 谱 系 障 碍（autism spectrum disorders， 儿童还表现为触