文档介绍:国际儿科学杂志 年 月第 卷第 期 Int J Pediatr Jun Vol. No.
2021 6 48 6 ꎬ 20 ꎬ
100191 China
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2 Autism Research Center Peking University Health Science Center Beijing 100191 China
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Corresponding author Wang Juan Email wjuan@ hsc􀆰 pku􀆰 edu􀆰 cn
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Abstract Autism spectrum disorder ASD is a group of highly heterogeneous neurodevelopmental
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disorders with different kinds of physiological dysfunctions. Based on the literature reports physiological dys ̄
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functions of ASD mainly focus on four aspects including immune dysregulation / inflammation oxidative
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stress mitochondrial dysfunction and environmental toxin exposure. This review focuses on the main manifes ̄
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tations of the four physiological abnormalities in patients with ASD aiming to illustrate the relationship between
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various physiological abnormalities and autism providing clues for the research treatment and prevention strat ̄