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孤独症谱系障碍生理功能异常的研究进展.pdf

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孤独症谱系障碍生理功能异常的研究进展.pdf

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文档介绍:国际儿科学杂志 年 月第 卷第 期 Int J Pediatr Jun Vol. No.
2021 6 48 6   ꎬ 20 ꎬ
100191 China

2 Autism Research Center Peking University Health Science Center Beijing 100191 China
ꎬ ꎬ ꎬ
Corresponding author Wang Juan Email wjuan@ hsc􀆰 pku􀆰 edu􀆰 cn
: ꎬ :
Abstract Autism spectrum disorder ASD is a group of highly heterogeneous neurodevelopmental
【 】   ( )
disorders with different kinds of physiological dysfunctions. Based on the literature reports physiological dys ̄

functions of ASD mainly focus on four aspects including immune dysregulation / inflammation oxidative
ꎬ ꎬ
stress mitochondrial dysfunction and environmental toxin exposure. This review focuses on the main manifes ̄

tations of the four physiological abnormalities in patients with ASD aiming to illustrate the relationship between

various physiological abnormalities and autism providing clues for the research treatment and prevention strat ̄