文档介绍：不同产地灵芝中三萜及甾醇的含量考察
林绍瑜胡晓文
(广东省农垦中心医院药剂科广东湛江 524000)
【摘要】目的:分析测定山东、安徽、浙江不同产地灵芝的三萜及甾醇含量。方法:以齐墩果酸为对照品,用紫外-可见分光光度法测定三萜及甾醇含量。结果:三萜及甾醇含量最高的为山东灵芝,其次为浙江灵芝,再次为安徽灵芝。结论:山东、安徽、浙江三产地灵芝中三萜及甾醇含量存在明显的差异。
【关键词】灵芝;三萜及甾醇;含量考察
【中图分类号】R24 【文献标识码】B 【文章编号】2095-1752(2016)04-0330-03
Determination of Triterpenoids and Sterol Content of Glossy ganoderma of different origin Lin Shaoyu , Hu Xiaowen.
Department of pharmacy, Guangdong Nongken Central Hospital, Guangdong Zhanjiang 524000, China.
【Abstract】Objective To analyse the triterpenoids and sterol content of Glossy ganoderma of different origin,such as Shandong, Anhui, Zhejiang and so on. Methods Oleanolic acid was used as a reference substance and ultraviolet-visible spec trophotometry was used to determine the triterpenoids and sterol content of Glossy ganoderma. Results The highest triterpenoids and sterol content of Glossy ganoderma is Shandong, next is Zhejiang and next is Anhui. Conclusion There are significant differences in the contents of triterpenoids and sterol of Glossy ganoderma in Shandong,Anhui and Zhejiang.
【Key words】Glossy ganoderma; Triterpenoids and Sterol; determination of content
灵芝是担子菌纲多孔菌科灵芝属真菌赤芝、紫芝的干燥子实体。灵芝主产于山东、安徽、浙江、吉林等地,具有扶正固本、健脾和胃、补益精气功能,能够调节和增强人体免疫力和预防心脑血管病[1-3]。三萜及甾醇是灵芝的主要有效成分,灵芝三萜具有抗HIV-1及HIV-1蛋白酶活性、保肝、抗肿瘤和抗艾滋病毒等药理活性[4-5]。不同来源的样品,其三萜甾醇的含量存在较大差异,本文测定三大主产地山东、安徽和浙江的灵芝三萜及甾醇含量,为评判不同产地灵芝品质及合理用药提供科学依据。
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