文档介绍：SUDDEN CARDIAC DEATH
Yuanxiu Chen, MD,
DEPT. OF CARDIOLOGY
RENMIN HOSPITAL
WUHAN UNIVERSITY
DEFINITION
Sudden cardiac death:unexpected natural death due to a cardiac cause within a short time period from the onset of symptoms in a person without any prior condition that would appear fatal
Key points
Time
≤1 hour (24hours) from the onset
Cardiac arrest Discontinuation of blood supply to brain
Die or survive
History of heart disease:
with or without
Pathophysiological Mechanism 病理生理机制
Life threaten arrhythmias arising from several pathological condition
Tachyarrhythmias
Bradyarrhythmias or asystolic arrest
Pulseless electrical activity,PEA
Tachyarrhythmias
快速性心律失常
Ventricular fibrillation 70% 心室颤动
Sustained ventricular tachycardia <2%
持续性室速
Bradyarrhythmias or asystolic arrest
缓慢性心律失常心搏停顿
Sinus asystole
Pulseless electrical activity,PEA
(无脉搏性电活动)
Electromechanical dissociation
(电机械分离)
EPIDEMIOLOGY(流行病学)
Incidence 发生率 300,000-400,000 yearly in USA
Account for >50% cardiac death
In China
no accurate figure
huge population
victims must might be numerous
Influence of Age, Race, and Gender
AGE 年龄 The incidence of sudden cardiac death increases with age, in both men and women as well as whites and nonwhites because of the higher prevalence of ischemic heart disease at older age