文档介绍：金海咽炎颗粒的研制及临床应用
黑龙江省食品药品审核查验中心黑龙江哈尔滨 150000
【摘要】目的:探讨金海咽炎颗粒的制备工艺、质量控制,并观察其疗效。方法:采用喷雾干燥一步制粒法制粒,用液相色谱技术进行质量研究和控制,临床观察分治疗组与对照组,治疗组总有效率在95%以上。结论:医院自制金海咽炎颗粒制备工艺先进,质量可控,疗效确切、未见不良反应。
【关键词】金海咽炎颗粒研制临床应用
The preparation and clinical application of Jinhai pharyngitis granules
QIN Jing
Heilongjiang Food and Drug Inspection Center,Harbin 150000,Heilongjiang,China
[Abstract] Objective To investigate the preparation process and quality control with Jinhai pharyngitis granules,and to observe its A spray drying step was taken for granulation. A liquid chromatography technology was adopted for the research and quality control. The clinical observation divided patients into treatment group and control group,and the total efficiency of the treatment group was above 95%. Conclusion The hospital-made Jinhai pharyngitis granules are prepared with advanced technology,controllable quality,curative effect whereas no adverse reaction.
[Key words] Jinhai pharyngitis granules,preparation technology,clinical application
【中图分类号】【文献标志码】A【文章编号】2096-0867(2016)-06-128-01
金海咽炎颗粒由我院制剂室开发研制,是在原咽炎汤剂经剂型改进而来,现介绍如下。
1 处方金银花、胖大海、板蓝根、葛根、天花粉、桔梗、北沙参、麦冬、桑叶、薄荷、陈皮、甘草、冰片。
2 制备工艺将上药材称准;冰片研细备用;金银花等12味加热煎煮3次,,滤过,合并滤液,,加95%乙醇使含醇量达45%,搅拌均匀,静置72小时,收集上清液,回收乙醇,,备用。以上述浓缩液为粘合剂,并将冰片、蔗糖粉的混合物置流化床制粒室气流分布板上,喷雾干燥制粒;过筛,整粒;分装、包装即得。
3 质量研究与控制
,味甜、清凉。
鉴