文档介绍:Structure-Based
Ligand Design
edited by Klaus Gubernator and Hans-Joachim Bohm
***@3 WILEY-VCH
Methods and Principles
in Medicinal Chemistry
Edited by
H. Kubinyi
H. Timmerrnan
Editorial Board
F. Darvas, T. Fujita, . Ganellin,
E Gualtieri, U. Hacksell, H.-D. Holtje,
G. Leclerc, R. Rekker, J.-K. Seydel,
D. Triggle, H. van de Waterbeemd
Structure-Based
Ligand Design
edited by
Klaus Gubernator
Hans-Joachim Bohm
8WILEY-VCH
Weinheim New York - Chichester Brisbane Singapore - Toronto
Series Editors:
Prof. Dr. Raimund Mannhold Prof. Dr. Hugo Kubinyi Prof. Dr. Hendrik Timmerman
Biomedical Research Center ZHVN,A 30 Faculty of Chemistry
Molecular Drug Research Group BASF AG Dept. of Pharmacochemistry
Heinrich-Heine-Universitat D-67056 Ludwigshafen Free University of Amsterdam
UniversitatsstraRe 1 Germany De Boelelaan 1083
D-40225 Dusseldorf NL-1081 HV Amsterdam
Germany herlands
Volume Editors:
Dr. Klaus Gubernator Dr. Hans-Joachim Bohm
CombiChem Inc. Hoffmann-La Roche AG
8050 Camino Santa Fe Pharma Research
San Diego, CA 92121 4002 Basel
USA Switzerland
This book was carefully produced. Nevertheless authors, editors and publisher do not warrant the
information contained therein to be free of errors Readers are advised to keep in mind that statements
data, illustrations, procedural details or other items may inadvertently be urate.
Library of Congress Card No. applied for.
British Library Cataloguing-in-PublicationData: A catalogue record for this book is available from the British
Library.
Deutsche Bihliothek Cataloguing-in-PublicationData:
Structure based ligand design I ed. by Klaus Gubernator ; Hans-Joachim Bohm. - Weinheim ;New York ;
Chichester ; Brisbane ; Singapore ; Toronto : Wiley-VCH, 1998
(Methods and principles in medicinal chemistry ; Vol. 6)
ISBN 3-527-29343-4
0 WILEY-VCH Verlag GmbH, D-69469 Weinheim (Federal Republic of Germany), 1998
Printed on acid-fr