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神经元和神经胶质细胞-胶质细胞.ppt

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神经元和神经胶质细胞-胶质细胞.ppt

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文档介绍:该【神经元和神经胶质细胞-胶质细胞 】是由【相惜】上传分享,文档一共【12】页,该文档可以免费在线阅读,需要了解更多关于【神经元和神经胶质细胞-胶质细胞 】的内容,可以使用淘豆网的站内搜索功能,选择自己适合的文档,以下文字是截取该文章内的部分文字,如需要获得完整电子版,请下载此文档到您的设备,方便您编辑和打印。Neuron:Supportingcells:CNS:neuroglia(glia)PNS:SchwanncellsandsatellitecellsFunctions:physicalsupportelectricalinsulationmetabolicexchangeblood-brainbarrierCompositionofNervousTissue整理课件TypesandFunctionsofGliaNameofGlialCellFunctionAstrocyte(Astroglia)Star-shapedcellsthatprovidephysicalandnutritionalsupportforneurons:1)cleanupbrain"debris";2)transportnutrientstoneurons;3)holdneuronsinplace;4)digestpartsofdeadneurons;5)regulatecontentofextracellularspaceMicrogliaLikeastrocytes,-dendrogliaProvidetheinsulation(myelin)(myelin)!ImportanceinnervoussystemfunctionisVASTLYunderestimated!Evidenceismounting:NurturingroleSignalingrole(Memory?)InflammationPaine!Neuroglia:DistinguishingFeatures整理课件PresenceoftightjunctionsbetweentheendothelialcellsparisontoothercellisthelackofpinocyticvesiclesSelectivepermeabilitytomoleculesbasedontheirmolecularweightandlipidsolubilityPresenceofspecificmarkersRichintwoenzymes:gammaglutamyltranspeptidase(GGTP)(foraminoacidtransport)andalkalinephosphatase(transportofphsopahteions):glucosetransporter(GLUT-1);endothelialbarrierantigen(EBA;unknownfunction)andantigenrecognizedbytheMRCOX-47monoclonalantibody(importantforcell-to-celladhesion);transferrinreceptor(transportofferricions)."processes",however,(10-50timesmore):整理课件NerveCells整理课件Neurons,Glia,ExtracellularSpace,andBlood整理课件municationPartnersSReceivingsignalsfromneighboringneuronsandrespondingtothemwithreleaseofneuroactivesubstancesExpressreceptorsforalmostallneurotransmittersandneuromodulatorsIncreaseofintracellularcalciumconcentrationmonresponsestoneuralactivityMetabolicallycoupledtoneuralactivity整理课件