文档介绍：题目名称:(英文) The role of antigen specificity in the binding of murine
monoclonal anti-DNA antibodies to microparticles from
apoptotic cells
(中文) 从凋亡细胞抗原特异性与鼠单克隆抗DNA抗
体结合微粒的作用
题目名称:(英文)Oral administration of live Shigella ine candidates in rhesus
monkeysshow no evidence petition for colonization and
immunogenicity between different serotypes
(中文)活志贺氏菌候选猕猴口服疫苗没有证据表明不同血清型之间
的定植性和免疫原性
题目名称:(中文) 犬细小病毒HL- 01 株的分离鉴定及VP2
基因真核表达质粒的
(英文)Construction of eukaryotic expression plasmid of VP2 gene and
identification of HL- 1 isolate of canine parvovirus
学生姓名: 学号:
院系专业: 教学班级:
硕士导师: 职称: 博导
研究方向: 病毒
2014年 1 月 5 日
The role of antigen specificity in the binding of murine monoclonal anti-DNA antibodies to microparticles from apoptotic cells
Name: Major:Preventive Veterinary Medicine
Tutor:
Abstract:Antibodies to DNA (anti-DNA) are the serological hallmark of systemic lupus erythematosus and markers of underlying immune system disturbances. These antibodies bind to both single-stranded and double-stranded DNA, mediating pathogenesis by forming plexes. As shown recently, DNA in blood exists in both free and particulate forms, with DNA representing an ponent of microparticles. Microparticles are membrane-bound vesicles containing nuclear molecules, released by membrane blebbing during cell death and activation. A panel of monoclonal NZB/NZW F1 anti