文档介绍:该【日蟾蜍它灵对VEGF诱导血管生成影响的研究 】是由【niuww】上传分享,文档一共【2】页,该文档可以免费在线阅读,需要了解更多关于【日蟾蜍它灵对VEGF诱导血管生成影响的研究 】的内容,可以使用淘豆网的站内搜索功能,选择自己适合的文档,以下文字是截取该文章内的部分文字,如需要获得完整电子版,请下载此文档到您的设备,方便您编辑和打印。日蟾蜍它灵对VEGF诱导血管生成影响的研究Title:TheEffectsofJapaneseToad(Bufojaponicus)ExtractonVEGF-InducedAngiogenesisAbstract:ThisstudyaimedtoinvestigatethepotentialeffectsofJapanesetoad(Bufojaponicus)extractonVascularEndothelialGrowthFactor(VEGF)-,--inducedangiogenesis,:Angiogenesis,theformationofnewbloodvesselsfrompre-existingvasculature,playsavitalroleinvariousphysiologicalprocesses,includingembryogenesis,woundhealing,,itisassociatedwithseveralpathologicalconditions,includingtumordevelopment,diabeticretinopathy,,excessiveangiogenesiscanleadtovariousdiseases,::Japanesetoads(Bufojaponicus),thedriedtoadswerecrushedandextractedwithasuitablesolvent,:Humanumbilicalveinendothelialcells(HUVECs),proliferationassay,andmigrationassaywereperformedtoinvestigatetheeffectsoftheextractonVEGF-:Asuitableanimalmodel,suchasamouseorchickchorioallantoicmembrane,wasusedtoevaluatetheeffectsoftheJapanesetoadextractonVEGF-,andtheangiogenicresponsewasevaluatedusinghistologicalanalysis,immunohistochemistry,:TheJapanesetoadextractsignificantlyattenuatedVEGF-inducedtubeformation,migration,-dependentinhibitoryeffectonVEGF-:ThefindingsofthisstudydemonstratethepotentialoftheJapanesetoadextractasananti--:Inconclusion,thisstudyprovidesevidenceforthepotentialoftheJapanesetoadextractasaneffectiveinhibitorofVEGF---relateddisorders,providingafoundationforfutureresearchinthisfield.