文档介绍:该【核仁因子Bms1l在斑马鱼肝脏发育过程中的功能研究 】是由【niuww】上传分享,文档一共【2】页,该文档可以免费在线阅读,需要了解更多关于【核仁因子Bms1l在斑马鱼肝脏发育过程中的功能研究 】的内容,可以使用淘豆网的站内搜索功能,选择自己适合的文档,以下文字是截取该文章内的部分文字,如需要获得完整电子版,请下载此文档到您的设备,方便您编辑和打印。核仁因子Bms1l在斑马鱼肝脏发育过程中的功能研究Title:FunctionalStudyoftheNucleolarFactorBms1linZebrafishLiverDevelopmentAbstract:ThenucleolarfactorBms1lplaysacrucialroleinribosomebiogenesis,,,-:plexandhighlyregulatedprocessthatinvolvesthecoordinatedgrowth,differentiation,andmaturationofhepatocytesandnon-,,,,,theroleofBms1linliverdevelopment,particularlyinzebrafish,:ToinvestigatethefunctionofBms1linzebrafishliverdevelopment,,hepatocytedifferentiationmarkers,andliver-,:WefoundthatBms1lknockdowninzebrafishembryosresultedinimpairedliverdevelopment,characterizedbyabnormallivermorphologyandreducedexpressionofliver-specificgenes,,hepatocytedifferentiationmarkers,suchasalpha-fetoproteinandcytokeratin19,,Bms1lknockdownledtodefectsinribosomebiogenesis,,:Inconclusion,,reducedexpressionofliver-specificgenes,-,ourfindingscontributetothebroaderunderstandingofliverdevelopmentandofferinsightsintopotentialtherapeuticstrategiesforliverdiseasesbasedontargetingBms1landribosomebiogenesis.