文档介绍：What Those of Us Who Are Not Pharmacologist Need To Know About Selection & Use of Antibiotics
The objective will be to help better understand:
1) how viruses and bacteria cause different diseases
2) how the antibiotics they use work
3) antibiotics role in treating diseases caused by different bugs
4) antibiotic classes … and what makes them different
5) why an antibiotic seems to work on some cattle & not others
6) how the other things we give sick cattle can influence an antibiotic's effectiveness
7) how to select a proper antibiotic for different diseases
8) how to know when to switch
9) which antibiotic would make a better choice when you need to switch if an animal doesn't respond
10) when to quit
1
Parts of the Puzzle
how viruses & bacteria cause different diseases
Antibiotics do not work on viruses because viruses are not alive
A virus injects its DNA into a living cell and has that cell reproduce more of the viral DNA. With a virus there is nothing to "kill," so antibiotics don't work on it.
Viruses take over living cells … make the cell do what the virus demands … then leaves … cell is weaken or dead
how viruses & bacteria cause different diseases
Bacteria are single-anisms
Bacteria produce chemicals that damage or disable cells body cells
Different types of antibiotics affects different bacteria in different ways
Disease sequence of events:
Susceptible animal exposed.
Incubation is the period (time) from the first replication of the disease causing biological agent until promise of the an(s) occurs causing loss of function of the an(s).
Primary viral BRD this averages 3 days.
Secondary bacterial BRD averages 3 to 5 days behind the initial viral infection.
Disease sequence of events:
Inflammation occurs in stages.
Early, the body diverts white blood cells and blood in to the affected area typically causing swelling of tissue, both cells and spaces between cells.
As the inflammation continues, loss of function of the a