文档介绍:Proceedings of the Ninth International
Symposium on Cyclodextrins
Santiago postela, Spain, May 31-June 3, 1998
Edited by
JJ. Torres Labandeira
and
. Vila-Jato
Department of Pharmacy and Pharmaceutical Technology,
University of Santiago postela,
Spain
KLUWER ACADEMIC PUBLISHERS
DORDRECHT / BOSTON / LONDON
A CLP. Catalogue record for this book is available from the Library of Congress.
ISBN 0-7923-5721-3
Published by Kluwer Academic Publishers,
. Box 17, 3300 AA Dordrecht, herlands.
Sold and distributed in North, Central and South America
by Kluwer Academic Publishers,
101 Philip Drive, Norwell, MA 02061, .
In all other countries, sold and distributed
by Kluwer Academic Publishers,
. Box 322, 3300 AH Dordrecht, herlands.
Printed on acid-free paper
The cover illustration displays the solid-state conformation of a-cycloaltrin (a-CA) in different
forms: the molecule adopts a conformation of 3-fold rotational symmetry with a unique alternating
sequence Of4C1 and 1C4 altropyranose chair geometries (upper left model, space group P63), resul-
ting in banana-shaped haride units, of which one is represented as a space-filling CPK-type
model (lower left entry). In the crystal lattice pact molecules are stacked in transposed lay-
ers (upper right, water molecules left off for clarity). Each a-CA molecule is embedded into a
matrix of 21 water molecules (lower right, view along the hexagonal c-axis). The space filling
models reveal a-CA to be devoid of a central 'through-going' cavity. The graphics were generated
using Brickmann's MOLCAD molecular modeling program; for further information see the web-
pages at ' 'S. Immel, .
Schmitt, and RW. Lichtenthaler: a-Cycloaltrin: Conformation and Properties in the Solid-State and
Aqueous Solution.', pp. 41-48 of this volume.
All Rights Reserved
© 1999 Kluwer Academic Publishers
No part of the material protected by this c