文档介绍：Manganese Catalysts in Homogeneous
Oxidation Reactions
Jelle Brinksma
This research project was supported financially by the anisation for
Scientific Research (NWO/CW)
RIJKSUNIVERSITEIT GRONINGEN
Manganese Catalysts in Homogeneous
Oxidation Reactions
Proefschrift
ter verkrijging van het doctoraat in de
Wiskunde en Natuurwetenschappen
aan de Rijksuniversiteit Groningen
op gezag van de
Rector Magnificus, dr. F. Zwarts,
in het openbaar te verdedigen op
vrijdag 11 oktober 2002
om uur
door
Jelle Brinksma
geboren op 30 augustus 1971
te Norg
Promotor: Prof. dr. . Feringa
Referent: Dr. R. Hage
missie: Prof. dr. . Engberts
Prof. dr. ir. . de Vos
Prof. dr. . de Vries
ISBN 90-367-1683-7
CONTENTS
CHAPTER 1
Introduction Oxidation Catalysis
Biomimetic oxidation catalysis 2
Catalytic epoxidation reactions 8
Oxidation reactions with oxygen 9
Oxidation reactions with (hydrogen) peroxide 13
Titanium-catalysed epoxidation reactions 14
Epoxidation reactions catalysed by plexes 14
Tungsten-catalysed oxidation reactions 16
Iron-based epoxidation catalysts 17
cis-Dihydroxylation catalysed by osmium tetroxide 18
Oxidation reactions catalysed by plexes 20
Oxidation reactions catalysed by manganese plexes 21
Research objectives and outline of this thesis 23
References 24
CHAPTER 2
plexes as Homogeneous Epoxidation Catalysts
Introduction 36
plexes in oxidation catalysis 40
Modified tptn and tpen ligands 43
Synthesis of the ligands 45
In situ prepared plexes as homogeneous
oxidation catalysts 47
Conclusions 51
Acknowledgements 51
Experimental section 52
References 60
CHAPTER 3
In Situ Prepared plexes as Homogeneous Catalysts for Epoxidation
Reactions with Hydrogen Peroxide
Introduction 66
Synthesis of the ligands 68
In situ prepared plexes as homogeneous
oxidation catalyst