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邻苯二甲醛合成研究工艺.doc

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邻苯二甲醛合成研究工艺.doc

上传人:liwenfei1314 2018/5/13 文件大小:274 KB

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邻苯二甲醛合成研究工艺.doc

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文档介绍:摘要
邻苯二甲醛(O-phthaleldehyde,简写为OPA),以前是一种重要的医药化工中间体,该中间体在***类生物碱、荧光计组***测定及医药检测方面有广泛的应用,而作为消毒剂应用的报道最早见于1994年,Alfa等通过评价OPA作为一种新型的高效消毒剂,与戊二醛相比,不仅具有光谱,高效和低腐蚀性的优点,还具有刺激性小,.
邻苯二甲醛的合成路线较多,但大多产率较低,.
以邻二(一******)苯为原料,在催化剂存在条件下与无水醋酸钠进行酯化反应,以***,分离水相,***氧化得到目的产物邻苯二甲醛.
关键词: 邻二(一******)苯; 邻苯二甲醇; 邻苯二甲醛
ABSTRACT
OPA (O-phthaleldehyde, abbreviated as OPA), before the medicine is an important chemical intermediate, intermediate in the alkaloid amine, histamine fluorometer medical testing and determination of a wide range of applications, as Application of disinfectant found in the report as early as 1994, Alfa, and so on through the evaluation of the OPA as a new type of highly efficient disinfectant, glutaraldehyde, not only has the spectrum, high efficiency and low corrosive advantages, but also has a small irritation, stability Good, and so on its own characteristics. Glutaraldehyde and the resistance of Mycobacterium turtle has a good effect to kill.
OPA's more synthetic route, but most of the low yield, the higher the cost. On the subject of the OPA's synthetic route to carry out the rough discussion.
O-to (a chloromethyl) benzene as raw materials in the catalyst under the conditions of the existence of water and sodium acetate for esterification to lindane as a solvent. Organic phase separation. Organic phase and water in the alkaline conditions Hydrolysis, with water separation, vacuum distillation was the second o-methyl. OPA to methanol as raw materials have been adopted by the nitric acid oxidation product of the purpose of the OPA.
Key words: o-(a-methyl)-o-b methanol OPA
目录
第一章文献综述
戊二醛的研究概况................................................................
邻苯二甲醛的研究概况.................................................................................................
邻苯二甲醛的特点..............................................................................................