文档介绍：UpToDate 循证医学数据库 内容说明以及使用操作
鄭如雅
6/28/2018
大纲
什么是UpToDate
UpToDate主要特点
Evidence Grading 证据等级
检索UpToDate
问题与讨论
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什么是UpToDate?
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填补空白
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UpToDate的主要特点
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使用UpToDate的医院
United States 美国
Johns Hopkins Hospital
Mayo Foundation
UCLC Medical Center
Massachusetts General Hospital
University of California, San Francisco Medical Center
Australia 澳大利亚
Queensland Health
Northern Sydney Health
Royal Perth Hospital
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亚洲使用UpToDate的医院
Singapore General Hospital
National University Hospital, Singapore
National Taiwan University Hospital
Chang Gung Memorial Hospital
Seoul National University Hospital, Korea
Yonsei University Medical Center, Korea
University of Malaya Medical Center, Malaysia
Penang Adventist Hospital, Malaysia
King Chulalongkorn Memorial Hospital, Thailand
Angkor Hospital for Children, Cambodia
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UpToDate的主要特点
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Evidence Grading 循据等级
In 2001, we began a collaboration with Gordon Guyatt, a world leader in EBM, and his colleagues in the international GRADE collaborative to implement a grading system for mendations
UpToDate grades specific treatment and screening mendations
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Evidence Grading 循据等级
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MENDATION GRADES 医嘱的强度
Grade 1
Strong mendation
Benefits clearly outweigh the risks and burdens (or vice versa) for most, if not all, patients
“We mend…”
Grade 2
Weaker mendation
Benefits and risks closely balanced and/or uncertain
“We suggest…”
EVIDENCE GRADES 证据的品质
Grade A
High Quality Evidence
Consistent evidence from randomized trials, or overwhelming evidence of some other form
Grade B
Moderate Quality Evidence
Evidence from randomized trials with important limitations, or very strong evidence of some other form
Grade C
Low Quality Evidence
Evidence from observational studies, unsystematic clinical observations, or from randomized trials with serious flaws