文档介绍：尿路感染大肠埃希菌耐药分析
闫雳
[作者单位]安徽省萧县人民医院检验科,235200
[摘要]目的:探讨尿路感染中大肠埃希菌的耐药性变迁,为临床合理用药提供试验依据。方法:对2008~2010年度尿标本检出的234份大肠埃希菌进行超广谱β-内酰***酶(ESBLs)检测和药敏试验,并对药敏结果进行分析。结果:大肠埃希菌的产酶率呈增高趋势;药敏结果显示大肠埃希菌除对亚***培南耐药率为0外,对其他常用抗菌药物均出现了不同程度的耐药性,且ESBLS(+)的细菌耐药率普遍高于ESBLs(-)细菌。结论:尿路感染的大肠埃希菌耐药现象严重,尤其是ESBLs(+)株,要不断加强耐药性检测,为临床合理用药提供参考。
[关键词] 尿路感染;大肠埃希菌;药敏试验;超广谱β-内酰***酶
[中图分类号] [文献标识码] A
The analysis of drug resistance of Escherichia coli in urinary tract infections
Yan Li
(Department of Clinical Laboratory,Xiaoxian People's Hospital,Xiaoxian Anhui 235200,China)
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[Abstract]Objective:To exploring the resistance changes of the Escherichia coli () in urinary tract infection, and provid proofs about the reasonable use of drugs in :Two hundred and thirty –foue strains of in 2008 to 2010 annual urine specimen with extended-spectrum β-lactamase (ESBLs) detection and drug susceptibility test,were detected,,and the drug susceptibility results were analyzed..Results:the rate of enzy production of showed a rising trend;the drug sensitivity test shows that the resistance exists in normal antibiotics was in different dgrees expect for Imipenem,,and the rate of medical resisitance in ESBLs(+) bacteria was higher than in ESBLs(-).Conclusions:The resistant of urinary tract infection which caused by E. coli.  especially in ESBLs (+) strains, is so serious. It should be str