文档介绍：Anemia in childhood (小儿贫血)
To understand features of hematopoiesis and
blood in children.
prehend clinical features, diagnosis and
therapy of anemia.
To understand the definition, grade division
and classification of anemia in children.
To master etiology, pathogeny, diagnosis,
therapy and prevention of nutritional iron
deficiency anemia and nutritional
megaloblastic anemia.
Disease of hematopoietic system
infantile anemia
(1)nutritional iron deficiency anemia(IDA)
(2)nutritional megaloblastic anemia
Primary/immunity thrombocytopenia Purpura(ITP)
Leukemia
haematogenesis of children
hematopoiesis --produced blood
extramedullary
 before birth and postnatal
 
mesoblast hepatic medullary
3-15w 6w-6ms 3ms
Embryo stage
Mesoblastic haematogenesis:3ws begin,8ws weaken, 12-15ws disappears。
liver:8ws begin,6months gradually weaken ,erythroblast、granular cell and megakaryocyte.
Embryo stage
3、spleen:12ws begin erythrocyte, granule ,
lymphocyte
4、Haematogenesis of an
gland:8ws nodes:11ws
Embryo stage
5、myelo-haematopoiesis:6mons
Haematogenesis function emphasis,make various kinds of blood cells,unique an after birth.
Haematopoiesis postnatal
1、marrow:
2、extramedullary:when requirement of haemopoiesis increase,liver、spleen、lymphadenectasis,hepatomegaly and splenomegaly, in circulating blood
immature erythrocytes and granulocytes .
Physiological haemolysis
Normal newborns have higher hemoglobin(HB) and hematocrit levels and a shortened survival period of the fetal RBCs contributes to the development of physiologic anemia.