文档介绍：2014NOF骨质疏松指南解读
江苏省中西医结合医院
内分泌代谢病院区
epidemiology
Since NOF first published the Guide in 1999, it has e increasingly clear that many patients are not being given appropriate information about prevention and many patients are not receiving appropriate testing to diagnose osteoporosis or establish osteoporosis risk.
Most importantly, many patients who have osteoporosis-related fractures are not being diagnosed with osteoporosis and are not receiving any of the FDA-approved, effective therapies.
Medical Impact
Fractures and plications are the relevant clinical sequelae of osteoporosis.
Fractures may be followed by full recovery or by chronic pain, disability and death
Hip fractures are associated with an to 36 percent excess mortality within one year, and followed by a -fold increased risk of future fractures.
Pathogenesis of Osteoporosis-Related Fractures
Risk Assessment
All postmenopausal women and men age 50 and older should be evaluated for osteoporosis risk in order to determine the need for BMD testing and/or vertebral imaging.
In general, the more risk factors that are present, the greater the risk of fracture.
Osteoporosis is preventable and treatable, but because there are no warning signs prior to a fracture, many people are not being diagnosed in time to receive effective therapy during the early phase of the disease.
T-Score
World anization (WHO) 骨质疏松诊断标准