文档介绍：Diarrhea Disease
The first affiliated hospital
SUN YAT-SEN university
Prof. Wang Huishen
王慧深
Major cause of children’s(﹤5y) death
in developing countries in 2002
ARI
diarrhea
Malaria
measles
AIDS
Disease in
perinatal stage
others
18%
25%
23%
4%
5%
10%
15%
WHO/UNICEF. Clinical management of acute diarrhea
Sources: The world health report 2003, WHO,Geneva.
General introduction
Classification
Predisposing factor
Etiology
Pathogenesis
Clinical manifestations
Clinical features of mon enteritis
Persistent diarrhea
Diagnosis
Differential Diagnosis
Treatment
Content
General introduction
mon disease in childhood
frequency and characters of stool
Ages 6m~2y 50% <1y
Seasons viral origins—late autumn and spring beginning bacterial origins—summer
noninfectious diarrhea— every season
Multiple sources and factors
General introduction
Classification
Predisposing factor
Etiology
Pathogenesis
Clinical manifestations
Clinical features of mon enteritis
Persistent diarrhea
Diagnosis
Differential Diagnosis
Treatment
Content
Causes
Course
Degree
Infectious diarrhea: virus,
bacterium, fungi, parasites
Noninfectious diarrhea: diet,
weather, others
Acute:<2w
persistent:2w2m
chronic:>2m
Mild: the times of stool
and character change
Severe: pany dehydration, electrolytes
abnormality and general toxicity symptoms
Classification
Gastric acid secretion , secretion and activity of enzyme , quality and quantity of diet change quickly.
Water metabolism ,tolerance of hydropenia ,easy to body fluid disorder.
Nerves, endocrine, circulation, liver and renal function: not mature, easy to digestive tract function disorder.
Predisposing factor-1
Development of infancy digestive system : not mature
Predisposing factor-2
Defense system: not mature
Three defense system ( ): microflora, epithelium, immunity