文档介绍：40例食管癌调强同步多西他赛+顺铂放化疗疗效分析
【摘要】目的探讨调强放疗同步多西他赛+顺铂治疗食管癌的疗效及毒副作用。方法回顾分析40例调强同步多西他赛+顺铂放化疗的食管癌患者。SPSS 17统计分析该组患者的近期疗效、局部控制率、生存率及毒性反应。结果该组病例病灶近有效率为95% .1、2 年生存率为80%、%,1、%、%,轻度放射性反应:食管炎95%,%,%。食管造影长度(c2=、 P=)为生存率影响因素。结论调强放疗治疗同步多西他赛+顺铂周方案治疗食管癌近期疗效和局部控制率较好,虽毒性反应增加但能耐受。
【关键词】食管癌调强放疗同期放化疗多西他赛
【Abstract】Purpose To investigate the curative effect and the toxic side effect of intensity-modulated radiotherapy concurrent with docetaxel plus cisplatin chemoradiotherapy。Methods Retrospective analysis treatment of 40 patients with esophageal cancer who accepted intensity-modulated radiotherapy concurrent with docetaxel plus cisplatin chemoradiotherapy. Analyzed the short-term effect, the local control rate, the survival rate and toxicity of these 40 patients with SPSS 17. Results The effective rate of short-term effect of the 40 cases is 95%,the local control rate for one-year and two-years is % and %, the survival rate for one-year and two-years is 80% and 64.
5%. Mildly radioactive reaction: Esophagitis 95%, respiratory reaction %, leukocytes %, length of esophagography(c2=,P=) was the influencing factors of survival rate. Conclusions For patients with esophageal cancer, intensity-modulated radiotherapy concurrent with docetaxel plus cisplatin chemoradiotherapy lead to better short-term effect and higher local control rat