凯时与晴尔治疗糖尿病周围神经病变疗效比较.txt

文档介绍：凯时论文:凯时与晴尔治疗糖尿病周围神经病变疗效比较
日期: 2010年12月28日
[摘要] 目的:观察并比较凯时、晴尔对糖尿病周围神经病变的治疗作用。方法:回顾性分析 5月~ 7月我院确诊的2型糖尿病合并周围神经病变患者80例,随机分为凯时治疗组44例,晴尔治疗组36例。观察两组治疗前后症状改善情况,并用肌电图测量神经传导速度。结果:两组用药后自觉症状及神经传导速度均有所改善,凯时组明显优于晴尔组(P<)。结论:凯时与晴尔治疗糖尿病周围神经病变均有效,且凯时的治疗效果优于晴尔,可作为治疗糖尿病周围神经病变的理想的药物。
[关键词] 凯时;晴尔;糖尿病;周围神经病变
[中图分类号] [文献标识码]B [文章编号]1673-7210(2010)11(c)-040-02
parison between Lipo PGE1 and Azagrel in treatment of diabetic peripheral neuropathy
YU Weidong
(The Second Rongfu Military Hospital in Jilin Province, Lishu 136500, China)
[Abstract] Objective: pare the clinical effect of Lipo pGE1 and Azagrel in treatment of diabetic peripheral neuropathy (DPN). Methods: 80 patients with DPN were divided into Lipo pGE1 group (n=44) and Azagrel group (n=36), they were given Lipo PGE1 or Azagrel for 2 weeks,and the curative effects pared. Results: The improvement of DPN symptoms and signs or nerve conduction speeds in Lipo PGE1 group were obviously better than those Azagrel group (P<). Conclusion: Lipo PGE1 and Azagrel are effective treatment methods of DPN, and Lipo PGE1 is better than Azagrel, and can be used as ideal drug in treatment of DPN.
[Key words] Lipo PGE1; Azagrel; Diabetes millitus; Peripheral neuropathy
糖尿病周围神经病变(diabeticperipheralneuropathy,DPN)是糖尿病最常见的慢性并发症之一,可累及感觉神经、运动神经及植物神经。临床上常常以肢体疼痛、麻木、发凉等感觉异常为主要表现,严重者可引起下肢坏疽,是糖尿病患者致残的常见因素。临床发病率高,据报道其患病率高达90%以上[1],其发病机制尚未完全阐述。