文档介绍：LC-PUFAs and Infant nutrition 长链多不饱和脂肪酸与婴儿营养
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Fatty acids in nutrition 脂肪酸营养
Vitamins and
trace elements 维生素与微量元素
Lipids脂肪
Nutrition 营养
Regulatory
Functions 调节功能
Essential fatty acids 必需脂肪酸
Proteins 蛋白质
Structural
Functions 结构功能
Minerals 矿物质
Carbohydrates 碳水化合物
Energy
Production 提供能量
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-Linolenic acid (n-3) family α-亚麻酸族(n-3)
eicosapentaenoic acid (EPA)二十碳五烯酸
docosahexaenoic acid (DHA)二十二碳六烯酸
Classification of fatty acids脂肪酸分类
Cis顺式
Trans反式
Fatty Acids 脂肪酸
Unsaturated 不饱和脂肪酸
Saturated饱和脂肪酸
Polyene多烯烃
Monoene 单烯烃
Essential (cis) 必需脂肪酸(顺式)
Linoleic acid (n-6) family 亚油酸(n-6)族
-linolenic acid (GLA) γ-亚麻酸 arachidonic acid (AA)花生四烯酸
Non-essential 非必需脂肪酸
Non-essential 非必需脂肪酸
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Shorthand notation of fatty acids 脂肪酸的简略符号
CX:Y,n-Z
X = number of carbon atoms 碳原子数
Y = number of double bonds 双键数
Z = position of first double bond
from methyl end 从***端起首个双键位置
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Structure of fatty acids Example 脂肪酸结构例子
2
4
6
10
12
14
16
8
3
CH
COOH
Linoleic acid = C18:2,n-6 亚油酸
Methyl end ***端
Carboxyl end 羧基端
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PUFA metabolism PUFA的代谢
Alpha-linolenic acid α-亚麻酸
18:3
n-3
Plants植物 Algae藻类
n-6
Linoleic acid亚油酸 18:2
20:3
Gamma- linolenic acid (GLA) γ-亚麻酸 18:3
Arachidonic acid (ARA) 花生四烯酸 20:4
22:4
22:5
18:4
20:4
Eicosapentaenoic acid (EPA) 二十碳五烯酸 20:5
22:5
Docosahexaenoic acid (DHA) 二十二碳六烯酸 22:6
6-Desaturase
6-去饱和酶
Elongase链延长酶
5-Desaturase 5-去饱和酶
Elongase链延长酶
3 Steps 3步
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Roles of PUFA PUFA的作用
Structure 结构
Energy 提供能量
Regulation 调节
PUFA
Cell membranes 细胞膜
Storage + supply 储存+供应
Chemical messengers (eicosanoids) 化学信号 (类二十碳酸,局部类激素物质)
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The evidence for a beneficial role of dietary ARA and DHA in infant nutrition婴儿营养中膳食ARA和DHA有益作用的证据
Suggestive evidence 启发性证据
Nervous tissue (brain, retina) is rich in ARA and DHA 神经组织(大脑、视网膜)富含ARA和DHA
Human milk is rich in ARA and DHA
母乳中富含ARA和DHA
ARA and DHA are actively transferred from the mother to the fetus through the placenta
母亲通过胎盘活跃地传递ARA和DHA到胎儿
LC-PUFA formula (wit