文档介绍：Menopause and Depression Experience in Treatment
e Linn, MD&PhD
Beijing 2012
Objectives
Menopause associated psychological changes and symptoms
Pathophysiology in Menopause Depression
Alternative Treatment options for bothersome symptoms ( Medications)
Medication for the women who is Contraindicated for Hormone
Depression in Menopause
Trend of Suicide in a woman’s Life
Two peak in all life of women
Adolescence and Menopause
Menopause symptom related psychotic disease (Depression)
Metabolism, Volume 54, Issue 5, Supplement, May 2005, Pages 49–52
Estrogen with Serotonin
1. Inhibit the Monoamine Oxidase (MAO) function
2. Moderate the serotonin (alpha 1) receptor effect
Darlene Deechera, From menarche to menopause: Exploring the underlying biology of depression in women experiencing hormonal changes, Psychoneuroendocrinology, Volume 33, Issue 1, January 2008, Pages 3–17
Serotonin in Menopause
Serotonin decrease it amount
Serotonin decrease it effect
Estrogen and Depression
Premenstrual Dysphoric Disorder (PMDD)
Post Partum Depression
Postmenopause Depression