骨髓间充质干细胞对雌性大鼠压力性尿失禁影响的研究.pdf

文档介绍：第三军医大学
硕士学位论文
骨髓间充质干细胞对雌性大鼠压力性尿失禁影响的研究
姓名:胡华
申请学位级别:硕士
专业:妇产科学
指导教师:梁志清
20040501
第三军医大学硕士学位论文
英文缩写一览表

简写英文名称中文名称
A Absorbance 吸光度
5-Aza-CR 5-azacytidine 5-氮杂胞苷
BSA bovine serum albumin 牛血清白蛋白
DAB 3,3-diaminobezidine 3 3-二氨基联苯胺
ddH2O double distilled water 双蒸水
DNA Deoxyribonuclease 脱氧核糖核酸
DEPC Diethyl pyrocaubonate 焦碳酸二乙酯
EP Eppendorf 微量离心管
FBS fetal bovine serum 胚牛血清
HSCs hematopoietic stem cell 造血干细胞
HRP Horseradish peroxidase 辣根过氧化物酶
MRFs Myogenic regulator factors 生肌调节因子
Myf5 Myogenic factor-5 生肌因子-5
MSCs mesenchymal stem cells 间充质干细胞
OD opeical density 光密度值
PBS Phosphate buffered saline 磷酸盐缓冲液
MTT 5-diphenyl tetrazolium bromide 四氮唑盐
SUI stress urinary incontinence 压力性尿失禁
TVT tension free vaginal tape 无张力阴道悬带术
UI urinary incontinence 尿失禁

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第三军医大学硕士学位论文
The Effect of bone marrow derived-mesenchymal Stem
Cells on Stress Urinary Incontinence of the female rats

Abstract

The stress urinary incontinence (SUI) is a disease that the urine flow outward without
orders when the patients have a sudden pressure to their abdomen such as
cough,laugh,cry,sneeze,raising heavy body. SUI mainly relate to the females in which the
rate is about 15 percent to 60 percent, which especially give a lot of trouble to the old
women. The SUI would be paid attention to with the ageing increasing on our society.
The injection therapy has the virtues of safety, simple, convenience, less wound and
easily practicing in out-patient service. The medicine or chemical reagents were injected
into the mucosa and muscle around the internal os near the urinary bladder to lengthen and
lessen the urethra. The resisting force of urinary can be increased and control the stress
urinary incontinence essfully.
At present the ideal material has not been discovered which have the virtues of better
longer effect, lower cost and safety. The idea material should have some characteristics as
following: no immunogenicity, no excl