文档介绍：新疆医科大学医学硕士学位论文
Experimental study on the impact of immediate implantation of ß-Tricalcium phosphate on alveolar ridge defect
Postgraduate:Ma Ying Supervisor: Associate Professor HeHuiyu
Abstract
Objects : To establish a rabbit animal model of alveolar ridge defect after tooth extraction,and to evaluate the impact of immediate implantation of ß-tricalcium phosphate on preventing the residual alveolar bone. Methods : Under the general anesthesia, the bilateral central incisors of rabbits were extracted, and ß-TCP was implanted immediately on one side as the experimental group, while the other side without implantion as control. Rabbits were killed after 4,8 and 12 length, width, height changes of extraction area of both sides were measureed by Vernier caliper .The change of trabecular bone were examined by X-ray . The interface between ß-TCP and the alveolar bone were observed by Scanning electron microscopy. The density of residual ridge was detected by Dual-energy X-ray Absorptiometry. The histopathological changes of the alveolar bone were observed on the HE : The width of alveolar ridges was significant different between the experimental group and the control group after 4week,8 week and 12
week after ß-TCP implantatio n(P﹤).The length of alveolar ridge was significantly
different at 8 week and 12week after implation(P﹤). The height of alveolar ridge
was significant ly different at 8 week and 12week after implatio(n
P﹤).The amount of
trabecula bone of experimental group were more than that of the control group showed by X-ray photography. The alveolar bone and ß-bined closely under scanning electron microscope; The density of bone scan showed it was significantly different (P﹤
)between the experimental group and control group. Histopathological observation
showed that 4w after extraction,bone mass was increasing markedly in the alveolar fossa,the deposition of new bone was continued,work became ,new bon