文档介绍：1、目标和结果不清晰。
   It is noted that your manuscript needs careful editing by someone with expertise in technical English editing paying particular attention to English grammar, spelling, and sentence structure so that the goals and results of the study are clear to the reader.
2、未解释研究方法或解释不充分。
◆ In general, there is a lack of explanation of replicates and statistical me
thods used in the study.
◆ Furthermore, an explanation of why the authors did these various experiments
should be provided.
3、对于研究设计的rationale:
   Also, there are few explanations of the rationale for the study design.
4、夸张地陈述结论/夸大成果/不严谨:
   The conclusions are overstated.  For example, the study did not show
   if the side effects from initial copper burst can be avoid with the polymer formulation.
5、对hypothesis的清晰界定:
   A hypothesis needs to be presented。
6、对某个概念或工具使用的rationale/定义概念:
   What was the rationale for the film/SBF volume ratio?
7、对研究问题的定义:
   Try to set the problem discussed in this paper in more clear,
   write one section to define the problem
8、如何凸现原创性以及如何充分地写literature review:
   The  topic  is  novel  but  the  application  proposed  is  not  so  novel.
9、对claim,如A>B的证明,verification:
   There is no parison of the algorithm with previously known work, so it is impossible to judge whether the algorithm is an improvement on previous work.
10、严谨度问题:
   MNQ is easier than the primitive PNQS, how to prove that.