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. FT-NMR Sample Preparation Guide
Overview:
A good 1H NMR sample contains about 10 mg pound. The solution should contain
no solids or ic impurities. Your deuterated NMR solvent should be free of water, and
your NMR spectrum should contain no solvent peaks.
Reference:
Zubrick page 295 is relatively useful, but you should follow the specifics in this handout.
Also, keep in mind that we won't be running continuous wave spectrometers, so you should
disregard any discussion of them.
NMR Solvents:
Typical deuterated solvents include chloroform (CDCl3), water (D2O), benzene (C6D6),
acetone (CD3C(O)CD3), acetonitrile (), and tetrahydrofuran (C4D8O). Chloroform is by far
the most popular and will be used exclusively in . The bottle of CDCl3 that you will use for
the course will be prepared by the TA. In the future, when you purchase bottles of CDCl3, you will
have to prepare