文档介绍：ChapterChapter 33 BloodBlood
Topics in This Chapter
IntroductionIntroduction (Self(Self --learning)learning)
PhysiologicalPhysiological HemostasisHemostasis
BloodBlood GroupsGroups andand BloodBlood TransfusionTransfusion
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PartPart 11 IntroductionIntroduction
(Self(Self --learning)learning)
•• BodyBody FluidFluid
•• position andand VolumeVolume ofof BloodBlood
•• PhysicalPhysical --ChemicalChemical PropertiesProperties ofof BloodBlood
(English textbook P. 150~151,
264~278, 347, 382, 392)
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PartPart 22
PhysiologicalPhysiological HemostasisHemostasis
(English textbook P. 419~429)
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. PhysiologicalPhysiological HemostasisHemostasis
H(a)emostasisH(a)emostasis :: HomeostasisHomeostasis
thethe physiologicalphysiological processprocess arrestingarresting bloodblood
leakageleakage whenwhen aa vesselvessel isis damageddamaged
IndexIndex —— BleedingBleeding TimeTime
thethe timetime fromfrom thethe startstart toto thethe arrestarrest ofof
bleedingbleeding 11 –– 33 minmin normallynormally
Process:Process:
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. VascularVascular constrictionconstriction
. FormationFormation ofof thethe
plateletplatelet plugplug
. FormationFormation ofof thethe bloodblood
clotclot (blood(blood coagulation)coagulation)
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SerumSerum
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TheThe rolerole ofof plateletsplatelets inin hemostasishemostasis
PlateletsPlatelets inin normalnormal statestate ActivedActived plateletsplatelets
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adhesionadhesion
plateletsplatelets ++ collagencollagen
thrombocytesthrombocytes activationactivation
ò adhesionadhesion releasingreleasing
GPIbGPIb ,, VWFVWF
ò releasingreleasing
55--HTHT ,, TXATXA 2 ,, ADPADP
PL,PL, I,I, V,V, XI,XI, XIIIXIII
ò aggregationaggregation
ò clotclot retractionretraction
aggregationaggregation
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