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Mitochondrial Disorder.ppt

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Mitochondrial Disorder.ppt

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Mitochondrial Disorder.ppt

文档介绍

文档介绍:Mitochondrial Disorder
Medical ics
1894,found in animal cell
1897,mitochondrion
1894,found in animal cell
1897,mitochondrion
1963,mtDNA
1894,found in animal cell
Structure of mtDNA
Anderson &
Cambridge sequence
1. Semi-independent
Complex
Subunits
Nuclear
mtDNA

41
34
7

4
4
0

11
10
1

13
10
3

14
12
2
83
70
13
ic Characteristics
1. Semi-independent
2. Non-universality of the ic code
ic Characteristics
Met
Ile
AUA
Met
Met
AUG
Stop
Arg
AGA
Stop
Arg
AGG
Trp
Stop
UGA
Trp
Trp
UGG
mtDNA
Universal code
Codon
Variations in the ic Code
1. Semi-independent
2. Non-universality of the ic code
3. Matrilineal inheritance
ic Characteristics
Matrilineal Inheritance