文档介绍：Risk factors for development of chronic rhinosinusitis in patients with allergic rhinitis.
Sedaghat AR1, Gray ST, Wilke CO, Caradonna DS.
Author information
1Department of Otolaryngology-Head and Neck Surgery, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA. ahmad_******@
Abstract
BACKGROUND:
Chronic rhinosinusitis (CRS) is a heterogeneous inflammatory condition of the sinonasal cavity. CRS may be preceded by other sinonasal inflammatory diseases including allergic rhinitis (AR). It is unclear what factors may predispose patients with AR to develop CRS.
METHODS:
We performed a retrospective review of all patients diagnosed with AR (and not CRS) that presented to an otolaryngology clinic at a tertiary care center as part of a multidisciplinary allergy evaluation between March 2004 and November 2011. Medical records were evaluated for clinicodemographic factors including age, gender, smoking history, asthma, gastroesophageal reflux disease (GERD), aspirin sensitivity, nasal polyposis, seasonal AR, perennial AR, categories of positive antigens on formal allergy testing, and the following sinonasal anatomic variants puted tomography (CT): infraorbital (Haller) cells, concha bullosa, frontal intersinus cells, and anterior ethmoid frontal recess cells. Patients who did not develop CRS after at least 4 years of follow-up were grouped into the AR