文档介绍：Biostatistics ()
Professor Zewei Luo
Dr Chenqi Lu
Telephone: 021-55665269
E-mail: ******@fudan.
******@fudan.
Office: 2309 Guanghua east Building
Major ponents
Course lectures
Exercises puter software (MiniTab)
Inter-course tests
Final examination
Reference
Text: An Introduction to Biostatistics
Thomas Glover & Kevin Mitchell
Copyright © 2002 Waveland Press
Reference Books
(1) Mather, K. (1973). Statistical Analysis in Biology Chapman & Hall.
(2) Elandt-Johnson, R. C. (1971). Probability Models and Statistical ics John Wiley & Sons.
Chapter 1. Introduction to Data Analysis
§. A general concept of Scientific Methods
Design and Evaluation of Experiments
Observation of a particular event
Statement of the problem
Formulation of a hypothesis
Design of the experiment
Making a Prediction
Statistics -- The subject which helps design and interpret experiments properly
collection
manipulation
summarization
analysis of experimental data
utilization of the data to test scientific hypotheses
Biostatistics (Biometry) – Statistics in Biosciences
§ concepts in Biostatistics
Population vs. Sample
Parameters Statistics
Descriptive measure
Variables & Data Types
Quantitative variables
(a). Continuous variables or interval data
(b). Discrete variables
2. Ranked (ordinal) variables
3. Categorical data
§ . Measure of Central Tendency
(1) Mean
Population Mean: if a population contains N entities whose measures are x1, x2, … xN, the arithmetic mean is given by
Sample Mean: if a sample collected from a population contains n observations: x1, x2, … xn, the sample mean is given by
An example demonstrating and
The population measures: 1,6,4,5,6,3,8,7 with N = 8
If a sample with n = 3 is randomly collected from the population, there are a total of 56 possible such samples. Of the samples,
Four have a mean of 5, equal to the population mean
The rest have a mean differing from the population mean
Average over all th