文档介绍：**etoMyMolecularBiologyClassYangYang(杨洋教授)HuazhongUniversityofSciencesandTechnology**MolecularBiologyoftheGene,6/E---al.(2008)PartI:icsPartII:MaintenanceoftheGenomePartIII:ExpressionoftheGenomePartIV:RegulationPartV:Methods**PartIII:ExpressionoftheGenomeThispartconcernedwithoneofthegreatestchallengesinunderstandingthegene-howthegeneisexpressed**Ch12:MechanismsoftranscriptionCh13:RNAsplicingCh14:TranslationCh15:odeCHAPTER7Translation(第七章翻译)**bination基因组的保持基因组的表达**Whatistranslation?--icinformationcontainedinmessengerRNA(mRNA)icinformation:nucleotidesinmessengerRNA(mRNA)protein:linearsequencesofaminoacidsinprotein**ThelanguageofmRNA:fouralphabet(A,G,C,U)Thelanguageofprotein:twentyalphabet(aminoacid)translation**DNA:5-ATGAGTAACGCG-33-TACTCATTGCGC-5NontemplatestrandtemplatestrandtranscriptionmRNA:5-AUGAGUAACGCG-3translationProtein:Met-Ser-Asn-Ala**TranslationextremelycostsInrapidgrowingbacterialcells,proteinsynthesisconsumes80%ofthecell’senergy50%ofthecell’sdryweightWhy?