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Approaches to automated creation of tissue engineering scaffolds.doc

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Approaches to automated creation of tissue engineering scaffolds.doc

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Approaches to automated creation of tissue engineering scaffolds.doc

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文档介绍:APPROACHES TO AUTOMATED CREATION OF TISSUE ENGINEERING SCAFFOLDS
Milan TRIFUNOVIĆ, Jelena MILOVANOVIĆ, Miroslav TRAJANOVIĆ, Nikola KORUNOVIĆ,
Miloš STOJKOVIĆ
Faculty of Mechanical Engineering, University of Niš, Aleksandra Medvedeva 14, Niš, Serbia
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Abstract: Tissue engineering (TE) is a relatively new field in biomedical engineering that is receiving much attention among the munity and the general public. One approach to promote the regeneration of new tissue is application of scaffolds as a template to guide the proliferation, growth and development of cells appropriately. Scaffolds internal structure plays an important role for this purpose. The process of creating customized scaffolds includes definition of the internal architecture suitable for the development of the desired tissue and creation of external geometry to match the geometry of fragment being replaced. This paper analyzes the approaches which aim to simplify and automate the process of creating customized scaffolds.
Key words: tissue, engineering, scaffold
INTRODUCTION
Tissue engineering is an interdisciplinary field that applies the principles of engineering and the life sciences toward the development of biological substitutes that restore, maintain, or improve tissue function [