文档介绍：基础医学
兔自体骨髓间充质干细胞移植覆盖骨膜修复关节软骨缺损:
与单纯骨膜覆盖及空白对照的比较*★
李鹏翠,卫小春,李兵
Rabbit autologous bone marrow mesenchymal stem cell transplantation and periosteal flap coverage for repair of articular cartilage defects: parison with periosteal flap coverage alone and blank control
Li Peng-cui, Wei Xiao-chun, Li Bing
Department of Orthopaedics, Second Hospital, Shanxi Medical University, Taiyuan 030001, Shanxi Province, China
Li Peng-cui★, Master, Technician-in-charge, Department of Orthopaedics, Second Hospital, Shanxi Medical University, Taiyuan 030001, Shanxi Province, China
lpc1977@
Supported by: the Youth Foundation Program of Second Hospital of Shanxi Medical University, No. 2008015*
Received: 2008-01-31
Accepted: 2008-08-20
山西医科大学第二医院骨科,山西省太原市 030001
李鹏翠★,女,1977年生,河北省临城县人,汉族,2005年山西医科大学毕业,硕士,主管技师,主要从事软骨损伤修复研究。
lpc1977@
山西医科大学第二医院院青年基金项目(2008
015)*
中图分类号:
文献标识码:A
文章编号:1673-8225
(2008)47-09319-04
收稿日期:2008-01-31修回日期:2008-08-20
(08-50-1-757/G·Q)
Abstract
BACKGROUND: Presently, cartilage defect is mainly treated by autologous cartilage transplantation, which cannot be accepted by patients. With development of tissue engineering, mesenchymal stem cells have been a hot focus in research. Most scholars believed that dynamic stress, hypoxia and some growth factors are advantageous factors for differentiation of bone marrow mesencymal stem cells into chondrocytes, wh