文档介绍：基础医学
骨髓间充质干细胞向神经元样细胞诱导分化过程中端粒酶的变化★◆
董贺1,于晓霞2,姜熔光1
Telomerase activity changes during the differentiation of bone marrow mesenchymal stem cells into neuron-like cells
Dong He1, Yu Xiao-xia2, Jiang Rong-guang1
1Department of Ophthalmology, Third People's Hospital, Dalian 116033, Liaoning Province, China; 2Pathobiology Key Laboratory of Ministry of Education, College of Preclinical Medicine, Jilin University, Changchun 130021, Jilin Province, China
Dong He★, Master, Physician, Department of Ophthalmology, Third People's Hospital, Dalian 116033, Liaoning Province, China
dongheyt@
Received: 2008-03-24
Accepted: 2008-04-30
1 大连市第三人民医院眼科,辽宁省大连市 116033;2吉林大学基础医学院病理生物学教育部重点实验室,吉林省长春市 130021
董贺★,男,1982年生,吉林省四平市人,汉族,2007年吉林大学毕业,硕士,医师,主要从事青光眼、视网膜疾病。
dongheyt@
中图分类号:
文献标识码:A
文章编号:1673-8225
(2008)43-08500-04
收稿日期: 2008-03-24
修回日期:2008-04-30
(542008032440036/
N·Q)
Abstract
BACKGROUND: It was reported that the changes in telomerase activities had close relationship with the application safe of tissue engineering. There were few researches about the telomerase activity and mechanism during the induction of human bone marrow mesenchymal stem cells (hBMSCs).
OBJECTIVE: To evaluate the telomerase activity during the differentiation of in vitro hBMSCs into neuron-like cells.
DESIGN, TIME AND SETTING: The cytology opening experiments were performed at the Experimenta