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胰岛素抵抗、糖尿病与冠心病.ppt

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胰岛素抵抗、糖尿病与冠心病.ppt

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胰岛素抵抗、糖尿病与冠心病.ppt

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文档介绍:EpidemiologyofInsulinResistance,DiabetesMellitus,andCoronaryHeartDiseaseCriteriafortheDiagnosisofDiabetesMellitusandHyperglycemia PlasmaGlucoseConcentration>(>126)>(>110)to<(<126)2-HourPost GlucoseLoadFasting GlucoseDiabetesMellitusImpairedGlucoseToleranceImpairedFastingGlucose>(>200)>(>140)to <(<200);21:1414- (Aged>20years) ,VA:AmericanDiabetesAssociation,1998:1-$ountsfor64%oftotalcostsOthersOphthalmic diseaseCardiovascular diseaseRenal diseaseNeurologic diseasePeripheral vascular diseaseAnnualCHDDeathsper1000PersonsKannelWB,;241:2035-:DMandCHDMortality 20-YearFollow-up178174MenWomenDMNon-DMIschemic heart disease%:; CausesofDeathOther heart diseaseDiabetesCancerStrokeInfectionOtherMortalityper1000 person-years**Age-;21:1138-(US)*Definedin1971-1975,followedupthrough1982-1984. **Definedin1982-1984,followedupthrough1992-;281:1291-*-%+%Men,cohort1*Men,cohort2**Women,cohort1*Women,cohort2**-%-%(P=)(P=)(P<)(P=)Rateper1000person-yearsWOMENMENSurvivalPost-MIinDiabeticandNondiabeticMenandWomen:;14:537-(%)MonthsPost-MINodiabetesn=228n=1628MonthsPost-MISurvival(%)0204060Diabetes100806040080020406080DiabetesNodiabetesn=156n=568WOMENMENCardi