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Drug screening strategy at post-genome era with Chinese traditional theory of materia medica.doc

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Drug screening strategy at post-genome era with Chinese traditional theory of materia medica.doc

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Drug screening strategy at post-genome era with Chinese traditional theory of materia medica.doc

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文档介绍:Drug screening strategy at post-genome era with Chinese traditional theory of materia medica
Xiao Ming Wang
Hubei College of Traditional Chinese Medicine
E-mail: shermanwang@, foxglove@
Abstract:
Section: #44. Philosophy of Nature
The author first gives the definition of a life. A life has five characteristics: grow, reproduce itself, adjust and repair itself, can be killed, age to die. He first explained why and how development of life. He concluded: life development consists three aspects: life species evolution, life type specialization, life level multiplication. He proposed a strategy to screen drug bioactivity and give an explanation of Chinese Traditional theory of Materia medica in modern concept. The best drug to treat a disease life consists of ponents or functions of Monarch drug, minister drug, assistant drug and guide drug.
1. Introduction
Drugs are very important substances for human survival on the earth. Human have long history using drugs to treat and prevent diseases. Approach to drug therapeutics was entirely empirical before the mid-19th century. Nowadays, there are about 6,000 chemical entity and 15,000 natural products had used as drugs. It is still a great challenge for us to find good drugs to treat some diseases today (antitumor. antiHIV). Drug discovery is an arduous job. More than 50,000 new pounds may be screened out mercial benefit clinical