文档介绍：plaint: 62-year-oldmanwithprogressiveshortnessofbreathoverthepast2yearsHistoryofPresentIllness: Twoyearsbeforepatientbeganhavingshortnessofbreath(SOB).,,&SurgicalHistory:unremarkableAllergies:PenicillinMedicines:Nifedipine,Furosemide,StatinFamilyHistory:NegativeforlungdiseaseorrheumatologicprocessesSocialHistory:30pack-yearscigaretteconsumptionandstopped15yearsearlierTravelHistory:NegativePhysicalExamination:General:wellappearingVitalSigns:BP:110/70,Pulse:85RR,26breaths/minuteHEENT:NoskintightnessaroundhismouthNeck:NojugularveindistentionCardiovascularSystem:NofindingsofpulmonaryhypertensionRespiratorySystem:InspiratorycracklesoverlowerhalfofchestExtremities:clubbingMusculoskeletalSystem:noarthritisorsynovitisLaboratoryWorkup: ANAnegative,speckledpatternwithanegativeSmantibody,negativeScl-70antibody;:FVC63%ofpredicted,FEV1/FVC85%DLCO30%ofpredictedTLC54%ofpredictedHRCTFINDINGSSlidecourtesyofGRaghu, (InterstitialLungDisease,ILD)北京医院呼吸科与危重症医学科许小毛什么是肺间质肺泡间及终末气道上皮以外的支持组织,包括血管及淋巴管组织。肺实质指各级支气管及肺泡结构。概述以肺泡壁为主并包括肺泡周围组织及其相邻支持结构病变的一组疾病群,病因近200种。由于病变不仅局限于肺泡间质,还可累及肺泡上皮细胞、肺毛细血管内皮细胞和细支气管,并常伴有肺实质受累如肺泡炎、肺泡腔内蛋白渗出等改变,故也称为弥漫性肺实质疾病(DiffuseParenchymalLungDisease,DPLD)