同步放化疗肺癌中文版.ppt

文档介绍：ManagementofunresectablestageⅢnon-smallcelllungcancer:binedchemoradiationintroductionUntilthelate1980s,thoracicradiationtherapy(TRT)?Sequentialchemoradiation?CALGB8433RT60GyPV2cycles+-,NEJM323:940-945,1990DillmanRO,JNCI88:1210-1215,1996RTOG8808RT60GyCT+RTH--yearsurvival4759522-yearsurvival2132243-yearsurvival1117145-,JNCI1995;87:198-205SauseW,CHEST2000;117:358-364OS<60ysurvivalFRANCERT65GyCT+-yearsurvival41502-yearsurvival14213-yearsurvival511Metastasisrate3826<-yearLCR1715ThierryLeChevaliar,JNCI1991;83:417-423CT:VCPC,vindesine,cyclophosphamide,cisplatin,lomustineConcurrentchemoradiation?Radiationalone?EORTCRT55PDD(W)+RTPDD(D)+RTNo3113113111-ysurvival4644542-ysurvival1319263---KoningC,NEJM1992;326:524-530