文档介绍：Clinical Neurophysiology 124 (2013) 1755–1764
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Clinical Neurophysiology
journal homepage: ate/clinph
Disrupted small-world work in children with Down Syndrome
a,b c, c c b,c
Mehran Ahmadlou , Masoud Gharib ⇑, Sahel Hemmati , Roshanak Vameghi , Firoozeh Sajedi
herlands Institute for Neuroscience, Amsterdam, Netherlands
b Dynamic Brain Research Institute, Tehran, Iran
c Pediatric Neurorehabilitation Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran
article info highlights
Article history:
The first study on anization of the functional brain connectivity (FBC) in DS.
Accepted 12 March 2013
FBC of the DS and normal children are topologically different in theta and alpha bands.
Available online 11 April 2013
The topological abnormalities are primarily in upper alpha within left hemisphere.
Keywords:
Down Syndrome
Electroencephalogram abstract
Functional brain connectivity
Objective: To explore how the anization or topology of the functional brain connectivity (FBC) is
Small-Worldness
Visibility Graph Similarity affected in Down Syndrome (DS).
Methods: As the brain is a work including numerous nonlinearly interacted neuronal
areas, the FBCs of typically developing (TD) children and DS patients puted using a nonlinear
synchronization method. Then the diff