文档介绍：常见肿瘤化疗方案肺癌SCLC一小细胞肺癌的化疗局限期1PE()、一线Cisplatin:60mg/m2d175mg/m2EtoposideVP-16:120mg/m2d1,2,中科院推荐33x4cycles周重复2CE()、一线Carboplatin:AUC65Etoposide:100mg/m2days1,2,34x4cycles中科院推荐周重复广泛期1PE()、一线Cisplatin:75mg/m2day1Etoposide:100mg/mdays1,2,33x4-6cycles周重复2CE()、一线Carboplatin:AUC65Etoposide:100mg/mdays1,2,34x4-6cycles中科院推荐周重复3IrinotecanCisplatin()PE、一线最新资料并不优于方案Irinotecan:60mg/m2d1,8,15Cisplatin:80mg/m2d24x4-6cycles周重复()二线目前尚无标准二线方案1<2-3mo,PS0-2:ifosfamide,paclitaxel,docetaxel,gemcitabine.、复发2>2-3mo6mo:topotecan,irinotecan,cyclophosphamide/doxorubicin/vincristine、复发(CAV),gemcitabine,taxane,oraletoposide,>6mo:.、复发可用原方案4、参加临床试验。中科院常用二线方案有1TI、PaclitaxelTAXOL135175mg/.Mesnad2-43异环磷酰胺保护周重复2NVB+IFO、VinorelbineNVB25mg/,8长春瑞宾IfosfamideIFO1200mg/-43异环磷酰胺保护周重复3CAO、CyclophosphamideCTX1000mg/.、.30mininfd1-53拓扑替康周重复SCLC其它化疗参考方案1CEV、CyclophosphamideCTX1000mg/.、CyclophosphamideCTX1000mg/-50mg/-16100-120mg/-33鬼臼乙叉甙周重复3VIP、EtoposideVP-1675mg/-4鬼臼乙叉甙IfosfamideIFO1200mg/-4异环磷酰胺保护CisplatinDDP20mg/-43顺铂周重复4Paclitaxel+Carboplatin、PaclitaxelTAXOL175mg/=、摘自Cisplatin80mg/m2d1etoposide80mg/mdays1,2,33周重复Cisplatin25mg/m2days1,2,3etoposide100mg/m2days1,2,33或周重复6Cyclophosphamide+doxorubicin+2005、摘自Cyclophosphamide1000mg/m2d1doxorubicin45mg/+doxorubicin+2005、摘自Cyclophosphamide1000mg/m2d1doxorubicin45mg/m2d1etoposide100mg/m2days1,2,2005、摘自Ifosfamide5000mg/m2d1(continuousinfusion,Mesna)etoposide75mg/m2d1,2,保护3,4carboplatin400mg/m2d1中科院同步放化疗常用方案VP16100mgd1~4,d29~32DDP50mgd1,8,29,36CBP:AUC4d1或NSCLC二非小细胞肺癌的化疗PS0~2PS2PS:3or4推荐化疗或老年人单药化疗不推荐化疗不排斥分子靶向治疗IRESSA如一线方案