文档介绍：结论:通过枸芪颗粒的工艺研究、质量标准研究、稳定性实验等研究,表明枸芪
颗粒工艺合理,质量标准可行,所制备的样品稳定、质量可控。
关键词枸芪颗粒;制备工艺;质量标准;稳定性;
Study on preparation process and quality standards of Gouqi
granules
Specialty: Traditional Chinese Medicine
Author:
Tutor:
Abstract
Objective: To study the literatures of Gouqi granules,preparation process and
quality standards, according to the relevant provisions of “Measures for the Administration
of Drug Registration ” and the technical guidelines on the study of Chinese medicine
natural medicines, and modern pharmacetic techniques are also applied into this
to the different physicochemical properties of effective ingredients, optimum
selection is adopted and a safe, effective , stable , controllable , easy to carry the modern
traditional Chinese medicine preparations were developed.
Methods: 1. To study the achievement of the position of lycium grain,
extract process and the pharmacological by the methods of Literature search Summary.
2. The Study on Preparation process: Use of alcohol extraction and water extraction
process of the application of industrial production to different polarity of medicinal
ingredients, selection of optimum by orthogonal design.
3. To established the TLC identification of Cycii Fructus、Ligustri Lucidi Fructus、
Astragali Radix、Ginseng Radix Rhizoma Rubra、Asinine Corii Colla、Crataegi Fructus.
4. Completed the Preliminary investigation of lycium grain, investigated the quality of
medicines on theunder of posite membrane packaging materials.
Results: the evaluation of astragaloside and dry extract yield ,optimized
extraction conditions of Ligustri Lucidi Fructus、Astragali Radix、Ginseng Radix Rhizoma
Rubra by Orthogonal design. Plus six times the amount of 60% ethanol extrsct, the first
three hours,the second is two hours, Optimized for 2 times to 6 times the amount of water
every two hours . The extract obtained liquid was concentrated to the relative de