46例新生儿呼吸窘迫综合征临床分析.doc

文档介绍：46例新生儿呼吸窘迫综合征临床分析
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作者:罗红芳,龙启煊,张芹,宋志梅
【摘要】目的:探讨新生儿呼吸窘迫综合征的治疗方法及疗效。方法:50例新生儿呼吸窘迫综合征患儿在常规治疗的基础上静脉注射盐酸氨溴索、多巴胺、酚妥拉明,45例给予鼻塞式持续气道正压(CPAP)吸氧,1例经气管插管机械通气。结果:50例患儿经治疗46例治愈,4例死亡。结论:采用盐酸氨溴索和多巴胺、酚妥拉明联合CPAP治疗轻、中度新生儿呼吸窘迫综合征效果较好。
【关键词】新生儿呼吸窘迫综合征; 持续气道正压;氨溴索;多巴胺;酚妥拉明
[ABSTRACT] Objective: To explore the treatment for neonatal respiratory distress syndrome. Methods: 50 neonatal respiratory distress syndrome cases were treated by intravenous injection of ambroxol, dopamine and phentolamine on the basis of routine treatment, of which 45 cases were supported with intranasal oxygen inhalation through continuous positive airway pressure (CPAP) and 1 case was given mechanical ventilation via tracheal tubing. Results: 46 out of 50 cases were cured, and four died. Conclusion: bined use of CPAP and ambroxol, dopamine and phentolamine has good effects on slight and mild neonatal respiratory distress syndrome.
[KEY WORDS] Neonatal respiratory distress syndrome; Oxygen inhalation through continuous positive airway pressure; Ambroxol; Dopamine; Phentolamine
新生儿呼吸窘迫综合征(NRDS)的发生原因有多种,其中最重要的是由于缺乏肺表面活性物质引起肺泡萎陷,主要发生在早生儿,临床上以进行性呼吸困难为主要表现,病理以出现伊红透明膜和肺不张为特征,又称肺透明膜病,研究显示盐酸氨溴索(ambroxol )能刺激肺泡Ⅱ型细胞合成及分泌表面活性物质,不同时机给予盐酸氨溴索可以达到预防和治疗NRDS的目的。本文对我院2005年10月~2008年10月收治的50例NRDS患者的临床资料进行回顾性分析,现报道如下。
1 临床资料
一般资料
本组NRDS患儿50例, 均符合NRDS的诊断[1]。胎龄 31~32周 12例,32~34周 16例,