文档介绍：HBeAg阴性慢性乙肝病毒携带者临床、肝脏病理、血清学检查五年回访
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作者:陈卫,陆忠华,邓俊,裴豪,朱银芳,丁虹,黄利华
【摘要】目的了解HBeAg阴性慢性乙肝病毒携带者的转归。方法对52例HBeAg阴性慢性乙肝病毒携带者进行了为期5年的临床症状、肝活检及血清学检查的动态观察研究。结果 5年间,52例HBeAg阴性慢性乙肝病毒携带者中有12例出现临床显性发病,%。其中13例行2次肝活检,原肝组织正常者几年内相对稳定,病理很少变化,原有病理改变者不易恢复。%。结论 HBeAg阴性慢性乙肝病毒携带者肝脏病理极大多数有异常,临床是否发病与肝脏炎症分级密切相关。
【关键词】 HBeAg阴性慢性乙肝病毒携带者肝活检肝脏病理
Abstract: Objective To understand the turnover of chronic asymptomatic carriers with HBsAg A 5 year dynamic observation and research on 52 chronic asymptomatic carriers with HBsAg negativity has been taken via viewing the clinical symptom, running liver biopsy and serological 12 of 52 patients, accounting for %, showed dominance morbidity. 13 patients received liver biopsy for the second time. We find that whose pathology of hepatic tissue was normal kept stable for several years while abnormal ones could hardly get recovery. The HBsAg darkening rate per year is
%.Conclusion The pathology of liver tissue for most chronic asymptomatic carriers with HBsAg negativity is abnormal, and whether falling to clinical ill is relevant to the classification of liver inflammation.
Keywords:chronic asymptomatic carrier with HBsAg negativity;liver biopsy;hepatic tissue pathology
,%~%会转变成显性乙型肝炎,部分隐匿进展甚至转变成肝硬化。人们常把此类人群分为“大三阳”和“小三阳”,即HBeAg