文档介绍：胺碘酮治疗急性心肌梗死室性心律失常180例临床报告
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作者:蔡飞, 李刚, 吴立群, 顾刚, 胡文英
【摘要】目的: 评价胺碘酮治疗急性心肌梗死(acute myocardial infarction,AMI)室性心律失常的疗效和安全性。方法: 观察180例AMI患者采用胺碘酮治疗室性心律失常的疗效和安全性,随访1年。结果: 反复发作的持续性室速、室颤患者,首剂3~5 mg/kg胺碘酮10 min内静脉注射;再以1~ mg/min维持,室速均被有效终止。以200 mg/d胺碘酮作为长期维持量能有效控制室性期前收缩。结论: 采用胺碘酮治疗AMI患者室性心律失常效果满意,安全可靠。
【关键词】胺碘酮; 急性心肌梗死; 室性心律失常; 随访
[Abstract] Objective: To evaluate the efficacy and safety of amiodarone in the treatment of ventricular arrhythmia in patients with acute myocardial infarction. Methods: One hundred and eighty patients with ventricular arrhythmia and acute myocardial infarction were treated with amiodarone and followed up one year. Results: Intravenous loading dose of 3~5 mg/kg amiodarone
was given within 10 minutes,followed by 1~ mg/min administration of amiodarone was effective in patients with recurrent sustained ventricular tachycardia and(or) maintenance amiodarone dose of 200 mg/d could control ventricular arrythmia. Conclusion: Amiodarone had high efficacy and was relatively safe for treating ventricular arrhythmia in patient with acute myocardial infarction.
[Key words] amiodarone; acute myocardial infarction; ventricular arrythmia; followup
近年来,胺碘酮已广泛应用于室性心律失常的治疗,短时间内静脉注射大剂量胺碘酮往往有效。特别是伴有心肌缺血,心功能不全者,可改善心肌缺血及心功能,降低心律失常死亡危险,耐受性好,不良反应少[1-3]。本文报告胺碘酮治疗180例急性心肌梗死(acute myocardial i