文档介绍:远端保护装置对急性心肌梗死患者介入治疗心肌的保护作用
作者:高延,李成祥,王海昌,贾国良,曹丰,冯旭阳
【关键词】急性心肌梗死
【Abstract】 AIM: To evaluate the safety and efficiency of distal protection device during primary angioplasty in acute myocardial infarction. METHODS: Seventytwo hospitalized acute myocardial infarction (AMI) patients in the Department of Cardiology of Xijing Hospital from June 2003-Mar 2004 were included in this study. The patients were divided into two groups of their own will: experimental group (n=39) with 36 males and l3 females, and control group (n=33) with 27 males and 6 females. Blood samples were collected from the elbow vein at 8, 16 and 24 h after percutaneous coronary intervention (PCI) and the serum level of cTnI and CKMB were measured. The difference of the incidence rate of cardiovascular events during the hospitalization between the two groups pared. RESULTS: ①The serum level of cTnI increased after PCI in both of the two groups, but that of experimental group reached peak at 8 h after PCI,while that of control group reached peak at 16 h after PCI. The serum levels of cTnI and CKMB were also significantly lower in experimental group than those in control group at 16 h and 24 h after PCI [cTnI 16 h (1201
±814) vs (693±624) μg/L, P<;24 h (1100±1868) vs (417±365) μg/L, P<. CKMB 16 h (±) vs (±) μkat/L, P<;24 h (±) vs (±) μkat/L, P<]. ② T