文档介绍:溃疡性结肠炎内镜、病理特点及其临床意义
作者:朱云,张南征,潘武,杜文琪
【关键词】溃疡性结肠炎
摘要:目的探讨溃疡性结肠炎内镜及病理组织学检查的临床特点及其意义。方法采用分级的方法描述219例活动期溃疡性结肠炎以及53例治疗后临床症状完全缓解者的内镜、病理组织学特点。运用Spearman等级相关系数进行相关分析。结果本组219例活动期溃疡性结肠炎内镜分级主要分布在Ⅱ~Ⅲ级,%。病理组织学分级主要分布在Ⅲ~Ⅳ级,%(r=,P=)。经治疗后4周~8个月间,53例临床症状完全消失。内镜分级由治疗前的Ⅲ~Ⅳ级向Ⅰ~Ⅱ级转归,而病理组织学分级Ⅳ%(r=,P=)。内镜分级与病理组织学分级两者间均无相关性。结论本组内镜及病理组织学分级描述溃疡性结肠炎病情以及疗效有不一致性。早期诊断以及近期疗效的判断不仅应依靠临床症状及内镜检查所见,更应结合病理组织学检查。
关键词:溃疡性结肠炎;分级;内镜;病理
Abstract:Objective To investigate the correlation between the grades of mucosal biopsy and endoscopy in patients with active ulcerative 219cases of ulcerative colitis and53treated cases were evaluated by grading pathology and r
esults were processed to calculate the Spearman correlation The correlation between en-doscopy grade and biopsy degree was(r=,P=)in the219cases of acute ulcerative colitis;and was(r=,P=)and(r=,P=)before and after the treatment respectively,in the53patients with clini-cal There is no correlation between clinical endoscopic and pathologic grades in active ulcerative coli- diagnosis and evaluation of therapy should be based on prehensive consideration of the endoscopic and pathologic findings and clinical manifestations.
Key words:ulcerative colitis;grade;endoscopy;pathology
溃疡性结肠炎(ulcerat