山西地区91 株淋球菌耐药性分析分析耐药株山西.doc

文档介绍：山西地区91株淋球菌耐药性分析
李玉串1, 李连青2, 戎建荣2 ,李桢1,叶峰山1,
(,山西太原030001;,山西太原030012)
【摘要】目的检测山西地区淋病奈瑟菌(NG)对5种抗生素的敏感性,分析其耐药特点。方法 K-B琼脂扩散法测定NG对抗生素的敏感性及用产色头孢噻吩法检测β-内酰胺酶。结果 91株淋球菌对青霉素、四环素、环丙沙星、%、%、%、O、%,检出质粒介导的产青霉素酶NG(PPNG)38株(%),%。结论青霉素、四环素及环丙沙星已不宜用于山西地区淋病的治疗;头孢曲松和大观霉素耐药率较低,可以作为山西地区治疗淋病的首选药物。但是大观霉素已出现耐药株,应引起重视。同时山西地区多重耐药现象十分严重,持续监测淋球菌的耐药性十分重要。
【关键词】淋病奈瑟菌;K-B琼脂扩散法;抗生素耐药率;β-内酰胺酶
Resistance Analysis of 91 strains of Neisseria gonorrhoeae in Shanxi
Li Yuchuan1,Li Lianqing2, Rong Jianrong2, Li Zhen1, Ye Fengshan1,
( Medical University,Taiyuan 030001,China; Clinical Laboratory,Taiyuan 030012,China)
【Abstract】 Objective To survey the antibiotic susceptibility and resistance trends of Neisseria gonorrhoeae to 5 Antibiotics in Shanxi .Methods The susceptibility to 5 antibiotic angents was tested by the disk diffusion method and β-lactamase determined by nitrocefin. Results The resistance rates of 91 strains to penicillin,tetracycline,ciprofloxacin,ceftriaxone,spectinomycin were %, %, %,0,%,penicillinase-producing neisseria gonorrhoeae(PPNG) accounted for % ,resistance rates of multiple-resistance isolates to 5 antibiotics were %.Conclusion penicillin, tetracycline, ciprofloxacin cannot be used as routine agents to treat gonorrhea, ceftriaxone and spectinomycin should