文档介绍:ObjectivesWhat’sanABG?UnderstandingAcid/BaseRelationshipGeneralapproachtoABGInterpretationClinicalcausesAbnormalABG’sCasestudiesTakehomeWhatisanABGArterialBloodGasDrawnfromartery-radial,brachial,-baseabnormalitiesWhatIsAnABG?pH [H+]PCO2PartialpressureCO2PO2PartialpressureO2HCO3BicarbonateBE BaseexcessSaO2 OxygenSaturationAcid/BaseRelationshipThisrelationshipiscriticalforhomeostasisSignificantdeviationsfromnormalpHrangesarepoorlytoleratedandmaybelifethreatening,tachycardic,’sShowPaCO2wellbelownl,pHabovenl,,tachycardic,’sShowPaCO2veryhigh, NaHCO3Carbonicacid basebicarbonateThesebuffersarelinkedtotherespiratoryandponentfunctionofthelungsCarbonicacidH2CO3Approximately98%normalmetabolitesareintheformofCO2CO2+H2OponentFunctionofthekidneysbasebicarbonateNaHCO3ProcessofkidneysexcretingH+intotheurineandreabsorbingHCO3-intothebloodfromtherenaltubules 1)activeexchangeNa+forH+betweenthetubularcellsandglomerularfiltrate 2)elerateshydration/dehydrationCO2inrenalepithelialcellsH2O+CO2H2CO3HCO3+H+Acid/BaseRelationship