药物性肝病71例临床分析.doc

文档介绍：:..药物性肝病71例临床分析作者:丁秋玲,朴熙绪单位:延边大学附属医院消化内科,吉林延吉【摘要】[背呆]探讨药物性肝病的病因及临床特点.[病例报告]采用冋顾性分析方法対71例药物性肝病住院患者的用夯史、临床衣现、(%),抗结核类药物为16例(%),抗生素类药物为13例(%),抗肿瘤药物为9例(%),解热镇痛药物为7例(%),抗甲状腺类药物为4例(%),中枢神经系统药物为2例(%),其他为3例(%).药物性肝病临床表现多样,,为30例(%),其次为肝细胞型,为28例(%),其他为混合型,为13例(1&3%).经停用致肝损伤药物及给予保肝等治疗,70例(%)预后良好,1例(%)发展为肝硬化.[讨论]药物性肝病多由中药、抗结核药及抗生素类药物引起,主要类型为胆汁淤积型,其次为肝细胞型;大多数药物性肝病预后良好,少数病例可发展为重症肝炎或肝彼化.【关键词】肝炎,慢性,药物性;胆汁淤积;预后Clinicalanalysisof71caseswithdruginducedliverdiseaseDINGQiuling,PIAOXixu*,LIChenghao,JINYongri,JINAihua(DepartmentofGastroenterology,AffiliatedHospitalofYanbianUniversity,Yanji133000,Jilin,China),clinicalmanifestation,laboratoryexamination,(%)oftraditionalChinesemedicine,16cases(%)ofantituberculous,13cases(%)ofantibiotics,9cases(%)ofantitumor,7cases(%)ofantipyreticanalgesic,4cases(%)ofantithyroid,2cases(%)ofcentralnervoussystemagentsand3cases(%)oftheothersin71casesofdruginducedliverdisease・Theclinicalmanifestationofdruginducedliverdiseasewasmultiplicityandhadnopartic